There Are New Drugs For Preventing And Treating Acute Migraine Attacks

There Are New Drugs For Preventing And Treating Acute Migraine Attacks    

They Have Pros And Cons Compared To The Triptans, The Most Popular Drugs For Migraine Treatment    

There are new treatments for migraine attacks and migraine prevention. The standard treatment 30 years ago, was based on aspirin and acetaminophen along with non-steroidal anti-inflammatory drugs (NSAIDs). Afterward, triptans were introduced which were more effective than analgesics. At that time, there was a concern about the vasoconstriction produced through time, which could affect people with cardiovascular diseases. However, there was a different knowledge of the pathophysiology of the acute coronary syndrome. It was thought before that vasoconstriction was associated with acute myocardial infarction. However, studies have shown that this condition is caused by ruptured plaques and local thrombin generation. Also, not every patient responded to them triptans. There are now our two new classes of drugs for an acute migraine attack. One of them is called ditans, and works on the serotonin receptor, and has no vasoconstrictive issues. The second type of drug is CGRP antagonists, which have proven to be less effective than triptans and work even for patients who have a contraindication for triptans. These are effective for migraine prevention but had unpleasant side effects. They are injected every 3 months and work in combination with traditional migraine prevention drugs. Even though these drugs have shown to be very effective to treat acute migraine attacks, it is not yet defined if they are superior or equivalent to triptans.https://justnoheadache.com/n6ug